TY  - GEN
AU  - Amatu,A
AU  - Barault,L
AU  - Moutinho,C
AU  - Cassingena,A
AU  - Bencardino,K
AU  - Ghezzi,S
AU  - Palmeri,L
AU  - Bonazzina,E
AU  - Tosi,F
AU  - Ricotta,R
AU  - Cipani,T
AU  - Crivori,P
AU  - Gatto,R
AU  - Chirico,G
AU  - Marrapese,G
AU  - Truini,M
AU  - Bardelli,A
AU  - Esteller,M
AU  - Di Nicolantonio,F
AU  - Sartore-Bianchi,A
AU  - Siena,S
TI  - Tumor MGMT promoter hypermethylation changes over time limit temozolomide efficacy in a phase II trial for metastatic colorectal cancer
SN  - 1569-8041
PY  - 2017///1226
KW  - Adult
KW  - Aged
KW  - Biomarkers, Tumor
KW  - blood
KW  - Biopsy
KW  - Colorectal Neoplasms
KW  - DNA Methylation
KW  - genetics
KW  - DNA Modification Methylases
KW  - DNA Repair Enzymes
KW  - Dacarbazine
KW  - administration & dosage
KW  - Disease-Free Survival
KW  - Female
KW  - Humans
KW  - Male
KW  - Middle Aged
KW  - Promoter Regions, Genetic
KW  - Temozolomide
KW  - Tumor Suppressor Proteins
N1  - Publication Type: Clinical Trial, Phase II; Journal Article
UR  - https://doi.org/10.1093/annonc/mdw071
ER  -