Dorward, Hilary S

Pharmacological blockade of aquaporin-1 water channel by AqB013 restricts migration and invasiveness of colon cancer cells and prevents endothelial tube formation in vitro. [electronic resource] - Journal of experimental & clinical cancer research : CR Feb 2016 - 36 p. digital

Publication Type: Journal Article

1756-9966

10.1186/s13046-016-0310-6 doi


Angiogenesis Inhibitors--chemical synthesis
Aquaporin 1--antagonists & inhibitors
Cell Movement--drug effects
Colonic Neoplasms--drug therapy
Dose-Response Relationship, Drug
Endothelial Cells--cytology
Gene Expression Regulation, Neoplastic--drug effects
HCT116 Cells
HT29 Cells
Human Umbilical Vein Endothelial Cells
Humans
In Vitro Techniques
Neoplasm Invasiveness
Small Molecule Libraries--chemical synthesis