Gardner, Rebecca

Acquisition of a CD19-negative myeloid phenotype allows immune escape of MLL-rearranged B-ALL from CD19 CAR-T-cell therapy. [electronic resource] - Blood 05 2016 - 2406-10 p. digital

Publication Type: Case Reports; Journal Article

1528-0020

10.1182/blood-2015-08-665547 doi


Antigens, CD19--genetics
Antineoplastic Combined Chemotherapy Protocols--therapeutic use
Bone Marrow--pathology
Chromosomes, Human, Pair 11--genetics
Clone Cells
Combined Modality Therapy
Female
Histone-Lysine N-Methyltransferase--genetics
Humans
Immunophenotyping
Immunotherapy, Adoptive
Infant
Leukemia, Myeloid, Acute--genetics
Lymphocyte Depletion
Middle Aged
Myeloid-Lymphoid Leukemia Protein--genetics
Neoplastic Stem Cells
Oncogene Proteins, Fusion--genetics
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma--genetics
Receptors, Antigen, T-Cell--immunology
Recurrence
Remission Induction
Salvage Therapy
T-Lymphocyte Subsets--immunology
Translocation, Genetic
Tumor Escape