Shukla, Samriddhi

Cucurbitacin B inhibits the stemness and metastatic abilities of NSCLC via downregulation of canonical Wnt/β-catenin signaling axis. [electronic resource] - Scientific reports Feb 2016 - 21860 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2045-2322

10.1038/srep21860 doi


A549 Cells
Animals
Blotting, Western
Carcinoma, Non-Small-Cell Lung--chemically induced
Cell Line, Tumor
Cell Movement--drug effects
Cell Proliferation--drug effects
Cell Transformation, Neoplastic--drug effects
Down-Regulation--drug effects
Epithelial-Mesenchymal Transition--drug effects
Female
Human Umbilical Vein Endothelial Cells
Humans
Immunoprecipitation
Lung Neoplasms--chemically induced
Mice
Microscopy, Fluorescence
Neovascularization, Physiologic--drug effects
Nitrosamines--toxicity
RNA Interference
RNA, Small Interfering--metabolism
Transforming Growth Factor beta1--pharmacology
Triterpenes--toxicity
Wnt Signaling Pathway--drug effects
Wnt3 Protein--antagonists & inhibitors
Wnt3A Protein--antagonists & inhibitors
beta Catenin--metabolism