Ndufc2 Gene Inhibition Is Associated With Mitochondrial Dysfunction and Increased Stroke Susceptibility in an Animal Model of Complex Human Disease. [electronic resource]
- Journal of the American Heart Association Feb 2016
Publication Type: Journal Article; Research Support, N.I.H., Extramural
2047-9980
10.1161/JAHA.115.002701 doi
Adenosine Triphosphate--metabolism Adult Age of Onset Animals Brain--enzymology Cell Line Chi-Square Distribution Databases, Genetic Disease Models, Animal Electron Transport Complex I--deficiency Gene Deletion Gene Expression Profiling--methods Gene Frequency Genetic Predisposition to Disease Heterozygote Humans Hypertension--complications Logistic Models Male Membrane Potential, Mitochondrial Middle Aged Mitochondria--enzymology Mitochondrial Diseases--enzymology Multivariate Analysis Odds Ratio Oligonucleotide Array Sequence Analysis Phenotype Polymorphism, Single Nucleotide Quantitative Trait Loci RNA Interference Rats, Inbred SHR Rats, Transgenic Risk Factors Stroke--enzymology Transfection