TY  - GEN
AU  - Brindisi,Margherita
AU  - Maramai,Samuele
AU  - Gemma,Sandra
AU  - Brogi,Simone
AU  - Grillo,Alessandro
AU  - Di Cesare Mannelli,Lorenzo
AU  - Gabellieri,Emanuele
AU  - Lamponi,Stefania
AU  - Saponara,Simona
AU  - Gorelli,Beatrice
AU  - Tedesco,Daniele
AU  - Bonfiglio,Tommaso
AU  - Landry,Christophe
AU  - Jung,Kwang-Mook
AU  - Armirotti,Andrea
AU  - Luongo,Livio
AU  - Ligresti,Alessia
AU  - Piscitelli,Fabiana
AU  - Bertucci,Carlo
AU  - Dehouck,Marie-Pierre
AU  - Campiani,Giuseppe
AU  - Maione,Sabatino
AU  - Ghelardini,Carla
AU  - Pittaluga,Anna
AU  - Piomelli,Daniele
AU  - Di Marzo,Vincenzo
AU  - Butini,Stefania
TI  - Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain
SN  - 1520-4804
PY  - 2016///0823
KW  - Animals
KW  - Arachidonic Acids
KW  - metabolism
KW  - Blood-Brain Barrier
KW  - Brain
KW  - Cell Membrane
KW  - Drug Design
KW  - Encephalomyelitis, Autoimmune, Experimental
KW  - drug therapy
KW  - Endocannabinoids
KW  - Glycerides
KW  - HEK293 Cells
KW  - Humans
KW  - Mice
KW  - Models, Molecular
KW  - Monoacylglycerol Lipases
KW  - antagonists & inhibitors
KW  - Multiple Sclerosis
KW  - Mutagenicity Tests
KW  - Neuralgia
KW  - chemically induced
KW  - Organoplatinum Compounds
KW  - Oxaliplatin
KW  - Pain
KW  - Permeability
KW  - Proteomics
KW  - Receptor, Cannabinoid, CB1
KW  - agonists
KW  - Receptor, Cannabinoid, CB2
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/acs.jmedchem.5b01812
ER  -