TY  - GEN
AU  - Nishikawa,Joy L
AU  - Boeszoermenyi,Andras
AU  - Vale-Silva,Luis A
AU  - Torelli,Riccardo
AU  - Posteraro,Brunella
AU  - Sohn,Yoo-Jin
AU  - Ji,Fei
AU  - Gelev,Vladimir
AU  - Sanglard,Dominique
AU  - Sanguinetti,Maurizio
AU  - Sadreyev,Ruslan I
AU  - Mukherjee,Goutam
AU  - Bhyravabhotla,Jayaram
AU  - Buhrlage,Sara J
AU  - Gray,Nathanael S
AU  - Wagner,Gerhard
AU  - Näär,Anders M
AU  - Arthanari,Haribabu
TI  - Inhibiting fungal multidrug resistance by disrupting an activator-Mediator interaction
SN  - 1476-4687
PY  - 2016///0315
KW  - Animals
KW  - Antifungal Agents
KW  - pharmacology
KW  - Binding Sites
KW  - drug effects
KW  - Candida glabrata
KW  - Candidiasis
KW  - drug therapy
KW  - DNA-Binding Proteins
KW  - genetics
KW  - Drug Resistance, Fungal
KW  - Drug Resistance, Multiple, Fungal
KW  - Fluconazole
KW  - Fungal Proteins
KW  - metabolism
KW  - Gene Expression Regulation, Fungal
KW  - Hydrazines
KW  - pharmacokinetics
KW  - Ketoconazole
KW  - Mediator Complex
KW  - chemistry
KW  - Mice
KW  - Models, Molecular
KW  - Nuclear Magnetic Resonance, Biomolecular
KW  - Protein Binding
KW  - Protein Structure, Tertiary
KW  - Saccharomyces cerevisiae Proteins
KW  - Thiourea
KW  - analogs & derivatives
KW  - Trans-Activators
KW  - Transcription Factors
KW  - Transcriptional Activation
KW  - Up-Regulation
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/nature16963
ER  -