Kim, Nayoung

Integrated genomic approaches identify upregulation of SCRN1 as a novel mechanism associated with acquired resistance to erlotinib in PC9 cells harboring oncogenic EGFR mutation. [electronic resource] - Oncotarget Mar 2016 - 13797-809 p. digital

Publication Type: Journal Article

1949-2553

10.18632/oncotarget.7318 doi


Animals
Apoptosis
Biomarkers, Tumor--genetics
Carcinogenesis
Carcinoma, Non-Small-Cell Lung--drug therapy
Cell Proliferation
Drug Resistance, Neoplasm--genetics
ErbB Receptors--antagonists & inhibitors
Erlotinib Hydrochloride--pharmacology
Genomics--methods
Humans
Lung Neoplasms--drug therapy
Male
Mice
Mice, Nude
Mutation
Nerve Tissue Proteins--genetics
Protein Kinase Inhibitors--pharmacology
RNA, Small Interfering--genetics
Signal Transduction
Tumor Cells, Cultured
Xenograft Model Antitumor Assays