TY - GEN AU - Calcaterra,Nicholas E AU - Hoeppner,Daniel J AU - Wei,Huijun AU - Jaffe,Andrew E AU - Maher,Brady J AU - Barrow,James C TI - Schizophrenia-Associated hERG channel Kv11.1-3.1 Exhibits a Unique Trafficking Deficit that is Rescued Through Proteasome Inhibition for High Throughput Screening SN - 2045-2322 PY - 2016///1226 KW - Bortezomib KW - pharmacology KW - Cell Membrane KW - metabolism KW - Drug Discovery KW - Ether-A-Go-Go Potassium Channels KW - chemistry KW - Gene Expression KW - HEK293 Cells KW - High-Throughput Screening Assays KW - Humans KW - Intracellular Space KW - Leupeptins KW - Mutation KW - Proteasome Endopeptidase Complex KW - Proteasome Inhibitors KW - Protein Interaction Domains and Motifs KW - Protein Isoforms KW - Protein Transport KW - Schizophrenia KW - genetics N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/srep19976 ER -