Calcaterra, Nicholas E

Schizophrenia-Associated hERG channel Kv11.1-3.1 Exhibits a Unique Trafficking Deficit that is Rescued Through Proteasome Inhibition for High Throughput Screening. [electronic resource] - Scientific reports Feb 2016 - 19976 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

2045-2322

10.1038/srep19976 doi


Bortezomib--pharmacology
Cell Membrane--metabolism
Drug Discovery
Ether-A-Go-Go Potassium Channels--chemistry
Gene Expression
HEK293 Cells
High-Throughput Screening Assays
Humans
Intracellular Space--metabolism
Leupeptins--pharmacology
Mutation
Proteasome Endopeptidase Complex--metabolism
Proteasome Inhibitors--pharmacology
Protein Interaction Domains and Motifs
Protein Isoforms
Protein Transport
Schizophrenia--genetics