TY - GEN AU - Lorza-Gil,Estela AU - Salerno,Alessandro G AU - Wanschel,Amarylis C B A AU - Vettorazzi,Jean F AU - Ferreira,Mônica S AU - Rentz,Thiago AU - Catharino,Rodrigo R AU - Oliveira,Helena C F TI - Chronic use of pravastatin reduces insulin exocytosis and increases β-cell death in hypercholesterolemic mice SN - 1879-3185 PY - 2016///0728 KW - Animals KW - Drug Administration Schedule KW - Exocytosis KW - drug effects KW - Female KW - Hydroxymethylglutaryl-CoA Reductase Inhibitors KW - toxicity KW - Hypercholesterolemia KW - genetics KW - Insulin KW - metabolism KW - Insulin-Secreting Cells KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Pravastatin KW - Receptors, LDL KW - deficiency N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.tox.2015.12.007 ER -