Lorza-Gil, Estela

Chronic use of pravastatin reduces insulin exocytosis and increases β-cell death in hypercholesterolemic mice. [electronic resource] - Toxicology Feb 2016 - 42-52 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1879-3185

10.1016/j.tox.2015.12.007 doi


Animals
Drug Administration Schedule
Exocytosis--drug effects
Female
Hydroxymethylglutaryl-CoA Reductase Inhibitors--toxicity
Hypercholesterolemia--genetics
Insulin--metabolism
Insulin-Secreting Cells--drug effects
Mice
Mice, Inbred C57BL
Mice, Knockout
Pravastatin--toxicity
Receptors, LDL--deficiency