TY  - GEN
AU  - Guo,Dong
AU  - Pan,Albert C
AU  - Dror,Ron O
AU  - Mocking,Tamara
AU  - Liu,Rongfang
AU  - Heitman,Laura H
AU  - Shaw,David E
AU  - IJzerman,Adriaan P
TI  - Molecular Basis of Ligand Dissociation from the Adenosine A2A Receptor
SN  - 1521-0111
PY  - 2016///0815
KW  - Adenosine A2 Receptor Antagonists
KW  - chemistry
KW  - Amino Acid Substitution
KW  - Binding Sites
KW  - Cell Membrane
KW  - Databases, Protein
KW  - HEK293 Cells
KW  - Humans
KW  - Hydrogen Bonding
KW  - Hydrophobic and Hydrophilic Interactions
KW  - Kinetics
KW  - Ligands
KW  - Models, Molecular
KW  - Molecular Conformation
KW  - Molecular Dynamics Simulation
KW  - Mutation
KW  - Radioligand Assay
KW  - Receptor, Adenosine A2A
KW  - Recombinant Proteins
KW  - Solubility
KW  - Triazines
KW  - Triazoles
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1124/mol.115.102657
ER  -