TY  - GEN
AU  - Bakhashab,Sherin
AU  - Ahmed,Fahad W
AU  - Schulten,Hans-Juergen
AU  - Bashir,Ayat
AU  - Karim,Sajjad
AU  - Al-Malki,Abdulrahman L
AU  - Gari,Mamdooh A
AU  - Abuzenadah,Adel M
AU  - Chaudhary,Adeel G
AU  - Alqahtani,Mohammed H
AU  - Lary,Sahira
AU  - Ahmed,Farid
AU  - Weaver,Jolanta U
TI  - Metformin improves the angiogenic potential of human CD34⁺ cells co-incident with downregulating CXCL10 and TIMP1 gene expression and increasing VEGFA under hyperglycemia and hypoxia within a therapeutic window for myocardial infarction
SN  - 1475-2840
PY  - 2016///1011
KW  - Angiogenesis Inducing Agents
KW  - pharmacology
KW  - Antigens, CD34
KW  - metabolism
KW  - Biomarkers
KW  - Cell Hypoxia
KW  - Cells, Cultured
KW  - Chemokine CXCL10
KW  - genetics
KW  - Dose-Response Relationship, Drug
KW  - Down-Regulation
KW  - Gene Expression Profiling
KW  - Human Umbilical Vein Endothelial Cells
KW  - drug effects
KW  - Humans
KW  - Hyperglycemia
KW  - drug therapy
KW  - Hypoglycemic Agents
KW  - Membrane Proteins
KW  - Metformin
KW  - Myocardial Infarction
KW  - Neovascularization, Physiologic
KW  - Oxidoreductases
KW  - Phenotype
KW  - Stem Cells
KW  - Tissue Inhibitor of Metalloproteinase-1
KW  - Up-Regulation
KW  - Vascular Endothelial Growth Factor A
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1186/s12933-016-0344-2
ER  -