TY - GEN AU - Ozaki,Kei-Ichi AU - Awazu,Midori AU - Tamiya,Mayuko AU - Iwasaki,Yuka AU - Harada,Aya AU - Kugisaki,Satomi AU - Tanimura,Susumu AU - Kohno,Michiaki TI - Targeting the ERK signaling pathway as a potential treatment for insulin resistance and type 2 diabetes SN - 1522-1555 PY - 2017///0612 KW - 3T3-L1 Cells KW - Adipocytes KW - drug effects KW - Adipokines KW - metabolism KW - Adiponectin KW - Animals KW - Benzamides KW - pharmacology KW - Blood Glucose KW - Chemokine CCL2 KW - Diabetes Mellitus, Type 2 KW - Diet, High-Fat KW - Diphenylamine KW - analogs & derivatives KW - Disease Models, Animal KW - Extracellular Signal-Regulated MAP Kinases KW - antagonists & inhibitors KW - Fatty Acids, Nonesterified KW - Glucose Tolerance Test KW - Hyperlipidemias KW - Immunoblotting KW - In Vitro Techniques KW - Insulin KW - Insulin Resistance KW - Interleukin-6 KW - Lipolysis KW - MAP Kinase Signaling System KW - Male KW - Mice KW - Protein Kinase Inhibitors KW - Real-Time Polymerase Chain Reaction KW - Receptors, Leptin KW - deficiency KW - Reverse Transcriptase Polymerase Chain Reaction KW - Signal Transduction KW - Triglycerides KW - Tumor Necrosis Factor-alpha N1 - Publication Type: Journal Article UR - https://doi.org/10.1152/ajpendo.00445.2015 ER -