TY - GEN AU - Harris,Philip A AU - King,Bryan W AU - Bandyopadhyay,Deepak AU - Berger,Scott B AU - Campobasso,Nino AU - Capriotti,Carol A AU - Cox,Julie A AU - Dare,Lauren AU - Dong,Xiaoyang AU - Finger,Joshua N AU - Grady,LaShadric C AU - Hoffman,Sandra J AU - Jeong,Jae U AU - Kang,James AU - Kasparcova,Viera AU - Lakdawala,Ami S AU - Lehr,Ruth AU - McNulty,Dean E AU - Nagilla,Rakesh AU - Ouellette,Michael T AU - Pao,Christina S AU - Rendina,Alan R AU - Schaeffer,Michelle C AU - Summerfield,Jennifer D AU - Swift,Barbara A AU - Totoritis,Rachel D AU - Ward,Paris AU - Zhang,Aming AU - Zhang,Daohua AU - Marquis,Robert W AU - Bertin,John AU - Gough,Peter J TI - DNA-Encoded Library Screening Identifies Benzo[b][1,4]oxazepin-4-ones as Highly Potent and Monoselective Receptor Interacting Protein 1 Kinase Inhibitors SN - 1520-4804 PY - 2016///0816 KW - Animals KW - Cell Line, Tumor KW - Crystallography, X-Ray KW - DNA KW - chemistry KW - Dose-Response Relationship, Drug KW - HT29 Cells KW - Humans KW - Isoxazoles KW - chemical synthesis KW - Mice KW - Models, Molecular KW - Molecular Structure KW - Oxazepines KW - Protein Kinase Inhibitors KW - Receptor-Interacting Protein Serine-Threonine Kinases KW - antagonists & inhibitors KW - Small Molecule Libraries KW - Structure-Activity Relationship KW - U937 Cells N1 - Publication Type: Journal Article UR - https://doi.org/10.1021/acs.jmedchem.5b01898 ER -