TY  - GEN
AU  - Cheng,Hsin-Lin
AU  - Lin,Chiao-Wen
AU  - Yang,Jia-Sin
AU  - Hsieh,Ming-Ju
AU  - Yang,Shun-Fa
AU  - Lu,Ko-Hsiu
TI  - Zoledronate blocks geranylgeranylation not farnesylation to suppress human osteosarcoma U2OS cells metastasis by EMT via Rho A activation and FAK-inhibited JNK and p38 pathways
SN  - 1949-2553
PY  - 2016///1230
KW  - Biological Transport
KW  - drug effects
KW  - Bone Density Conservation Agents
KW  - pharmacology
KW  - Bone Neoplasms
KW  - drug therapy
KW  - Cadherins
KW  - metabolism
KW  - Cell Line, Tumor
KW  - Cell Movement
KW  - Cell Survival
KW  - Diphosphonates
KW  - Diterpenes
KW  - Epithelial-Mesenchymal Transition
KW  - Farnesol
KW  - Focal Adhesion Kinase 1
KW  - Focal Adhesion Protein-Tyrosine Kinases
KW  - Humans
KW  - Imidazoles
KW  - JNK Mitogen-Activated Protein Kinases
KW  - MAP Kinase Signaling System
KW  - Neoplasm Invasiveness
KW  - pathology
KW  - Nuclear Proteins
KW  - Osteoporosis
KW  - chemically induced
KW  - Osteosarcoma
KW  - Phosphorylation
KW  - Prenylation
KW  - Proto-Oncogene Proteins pp60(c-src)
KW  - Snail Family Transcription Factors
KW  - Twist-Related Protein 1
KW  - Zoledronic Acid
KW  - cdc42 GTP-Binding Protein
KW  - p38 Mitogen-Activated Protein Kinases
KW  - rho-Associated Kinases
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.18632/oncotarget.7138
ER  -