TY - GEN AU - Shi,Jianliang AU - Zuev,Dmitry AU - Xu,Li AU - Lentz,Kimberley A AU - Grace,James E AU - Toyn,Jeremy H AU - Olson,Richard E AU - Macor,John E AU - Thompson,Lorin A TI - Design and optimization of tricyclic gamma-secretase modulators SN - 1464-3405 PY - 2016///1005 KW - Amyloid Precursor Protein Secretases KW - antagonists & inhibitors KW - Aniline Compounds KW - chemical synthesis KW - Animals KW - Dose-Response Relationship, Drug KW - Drug Design KW - Humans KW - Mice KW - Molecular Structure KW - Protease Inhibitors KW - Structure-Activity Relationship KW - Triazines N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.bmcl.2015.06.020 ER -