Toby, Garabet G

Recombinant Factor IX Fc Fusion Protein Maintains Full Procoagulant Properties and Exhibits Prolonged Efficacy in Hemophilia B Mice. [electronic resource] - PloS one 2016 - e0148255 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0148255 doi


Animals
Antithrombin III--pharmacology
Blood Coagulation--drug effects
Blood Coagulation Tests
Coagulants--pharmacology
Disease Models, Animal
Enzyme Activation--physiology
Factor IX--genetics
Factor VIIa--pharmacology
Factor XIa--pharmacology
Half-Life
Hemophilia B--drug therapy
Hemorrhage--drug therapy
Immunoglobulin Fc Fragments--genetics
Mice
Mice, Inbred C57BL
Recombinant Fusion Proteins--genetics
Thrombin--biosynthesis