TY - GEN AU - Simpson,Jodie L AU - Carroll,Melanie AU - Yang,Ian A AU - Reynolds,Paul N AU - Hodge,Sandra AU - James,Alan L AU - Gibson,Peter G AU - Upham,John W TI - Reduced Antiviral Interferon Production in Poorly Controlled Asthma Is Associated With Neutrophilic Inflammation and High-Dose Inhaled Corticosteroids SN - 1931-3543 PY - 2016///0719 KW - Administration, Inhalation KW - Adrenal Cortex Hormones KW - administration & dosage KW - Adult KW - Aged KW - Aged, 80 and over KW - Asthma KW - drug therapy KW - Chemokine CXCL10 KW - immunology KW - Cross-Sectional Studies KW - Enzyme-Linked Immunosorbent Assay KW - Female KW - Forced Expiratory Volume KW - Glucocorticoids KW - HeLa Cells KW - Humans KW - Interferon-alpha KW - Interferon-beta KW - Interleukin-1beta KW - Interleukin-6 KW - Interleukin-8 KW - Leukocytes, Mononuclear KW - drug effects KW - Male KW - Middle Aged KW - Neutrophils KW - Rhinovirus KW - Severity of Illness Index KW - Sputum KW - cytology KW - Vital Capacity KW - Young Adult N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.chest.2015.12.018 ER -