TY - GEN AU - Jia,Yong AU - Juarez,Jose AU - Li,Jie AU - Manuia,Mari AU - Niederst,Matthew J AU - Tompkins,Celin AU - Timple,Noelito AU - Vaillancourt,Mei-Ting AU - Pferdekamper,AnneMarie Culazzo AU - Lockerman,Elizabeth L AU - Li,Chun AU - Anderson,Jennifer AU - Costa,Carlotta AU - Liao,Debbie AU - Murphy,Eric AU - DiDonato,Michael AU - Bursulaya,Badry AU - Lelais,Gerald AU - Barretina,Jordi AU - McNeill,Matthew AU - Epple,Robert AU - Marsilje,Thomas H AU - Pathan,Nuzhat AU - Engelman,Jeffrey A AU - Michellys,Pierre-Yves AU - McNamara,Peter AU - Harris,Jennifer AU - Bender,Steven AU - Kasibhatla,Shailaja TI - EGF816 Exerts Anticancer Effects in Non-Small Cell Lung Cancer by Irreversibly and Selectively Targeting Primary and Acquired Activating Mutations in the EGF Receptor SN - 1538-7445 PY - 2016///0725 KW - Animals KW - Antineoplastic Agents KW - pharmacology KW - Carcinoma, Non-Small-Cell Lung KW - drug therapy KW - Cell Line, Tumor KW - Drug Resistance, Neoplasm KW - drug effects KW - ErbB Receptors KW - metabolism KW - Female KW - Lung Neoplasms KW - Mice KW - Mice, Nude KW - Mutation KW - Phosphorylation KW - Rats KW - Xenograft Model Antitumor Assays KW - methods N1 - Publication Type: Journal Article UR - https://doi.org/10.1158/0008-5472.CAN-15-2581 ER -