TY - GEN AU - Francis,Kevin AU - Sapienza,Paul J AU - Lee,Andrew L AU - Kohen,Amnon TI - The Effect of Protein Mass Modulation on Human Dihydrofolate Reductase SN - 1520-4995 PY - 2016///0726 KW - Algorithms KW - Biocatalysis KW - Carbon Isotopes KW - Deuterium KW - Enzyme Stability KW - Humans KW - Isotope Labeling KW - Models, Molecular KW - Molecular Dynamics Simulation KW - Molecular Weight KW - Nitrogen Isotopes KW - Protein Conformation KW - Quantum Theory KW - Recombinant Proteins KW - chemistry KW - Temperature KW - Tetrahydrofolate Dehydrogenase N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1021/acs.biochem.5b00945 ER -