Layton, Mark E <br/><br/>
Discovery of 5-aryl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-ones as positive allosteric modulators of metabotropic glutamate subtype-2 (mGlu2) receptors with efficacy in a preclinical model of psychosis.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  Feb 2016 
 - 1260-4 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1464-3405 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2016.01.021  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Allosteric Regulation<br/>Animals<br/>Disease Models, Animal<br/>Drug Evaluation, Preclinical<br/>Imidazoles--blood<br/>Locomotion--drug effects<br/>Protein Binding<br/>Psychotic Disorders--drug therapy<br/>Pyridines--chemistry<br/>Pyridones--blood<br/>Rats<br/>Receptors, Metabotropic Glutamate--chemistry<br/>Structure-Activity Relationship