TY - GEN AU - Naguib,Youssef W AU - Lansakara-P,Dharmika AU - Lashinger,Laura M AU - Rodriguez,B Leticia AU - Valdes,Solange AU - Niu,Mengmeng AU - Aldayel,Abdulaziz M AU - Peng,Lan AU - Hursting,Stephen D AU - Cui,Zhengrong TI - Synthesis, Characterization, and In Vitro and In Vivo Evaluations of 4-(N)-Docosahexaenoyl 2', 2'-Difluorodeoxycytidine with Potent and Broad-Spectrum Antitumor Activity SN - 1476-5586 PY - 2016///1020 KW - Animals KW - Antimetabolites, Antineoplastic KW - chemical synthesis KW - Calorimetry, Differential Scanning KW - Cell Line, Tumor KW - Cell Survival KW - drug effects KW - Deoxycytidine KW - analogs & derivatives KW - Disease Models, Animal KW - Dose-Response Relationship, Drug KW - Drug Stability KW - Female KW - Humans KW - Mice KW - Mice, Transgenic KW - Solubility KW - X-Ray Diffraction KW - Xenograft Model Antitumor Assays KW - Gemcitabine N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.neo.2015.11.012 ER -