TY - GEN AU - Shim,Joong Sup AU - Li,Ruo-Jing AU - Bumpus,Namandje N AU - Head,Sarah A AU - Kumar Pasunooti,Kalyan AU - Yang,Eun Ju AU - Lv,Junfang AU - Shi,Wei AU - Liu,Jun O TI - Divergence of Antiangiogenic Activity and Hepatotoxicity of Different Stereoisomers of Itraconazole SN - 1557-3265 PY - 2018///0122 KW - Angiogenesis Inhibitors KW - chemistry KW - Animals KW - Cell Line, Tumor KW - Cholesterol KW - metabolism KW - Coculture Techniques KW - Female KW - Hepatocytes KW - drug effects KW - Human Umbilical Vein Endothelial Cells KW - Humans KW - Inhibitory Concentration 50 KW - Itraconazole KW - Liver KW - Male KW - Mice, Inbred BALB C KW - Mice, Nude KW - Middle Aged KW - Neovascularization, Physiologic KW - Pericytes KW - Protein Processing, Post-Translational KW - Stereoisomerism KW - Vascular Endothelial Growth Factor Receptor-2 KW - Xenograft Model Antitumor Assays KW - Young Adult N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/1078-0432.CCR-15-1888 ER -