TY  - GEN
AU  - Perng,Daw-Shyong
AU  - Tsai,Yu-Hsin
AU  - Cherng,Jonathan
AU  - Wang,Jeng-Shing
AU  - Chou,Kuo-Shen
AU  - Shih,Chia-Wen
AU  - Cherng,Jaw-Ming
TI  - Discovery of a novel anticancer agent with both anti-topoisomerase I and II activities in hepatocellular carcinoma SK-Hep-1 cells in vitro and in vivo: Cinnamomum verum component 2-methoxycinnamaldehyde
SN  - 1177-8881
PY  - 2016///1011
KW  - Acrolein
KW  - analogs & derivatives
KW  - Animals
KW  - Antineoplastic Agents, Phytogenic
KW  - isolation & purification
KW  - Apoptosis
KW  - drug effects
KW  - Carcinoma, Hepatocellular
KW  - drug therapy
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Cinnamomum zeylanicum
KW  - chemistry
KW  - DNA Topoisomerases, Type I
KW  - DNA Topoisomerases, Type II
KW  - Dose-Response Relationship, Drug
KW  - Humans
KW  - Liver Neoplasms
KW  - Male
KW  - Membrane Potential, Mitochondrial
KW  - Mice
KW  - Mice, Inbred BALB C
KW  - Mice, Nude
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.2147/DDDT.S93599
ER  -