TY  - GEN
AU  - Wai,Timothy
AU  - García-Prieto,Jaime
AU  - Baker,Michael J
AU  - Merkwirth,Carsten
AU  - Benit,Paule
AU  - Rustin,Pierre
AU  - Rupérez,Francisco Javier
AU  - Barbas,Coral
AU  - Ibañez,Borja
AU  - Langer,Thomas
TI  - Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice
SN  - 1095-9203
PY  - 2016///0202
KW  - Animals
KW  - Cardiomyopathy, Dilated
KW  - genetics
KW  - Diet, High-Fat
KW  - Embryonic Development
KW  - Female
KW  - GTP Phosphohydrolases
KW  - Gene Deletion
KW  - Heart
KW  - embryology
KW  - Heart Failure
KW  - Male
KW  - Metalloendopeptidases
KW  - Metalloproteases
KW  - Mice
KW  - Mice, Knockout
KW  - Mitochondria, Heart
KW  - metabolism
KW  - Mitochondrial Dynamics
KW  - Mitochondrial Proteins
KW  - Mitophagy
KW  - Muscle, Skeletal
KW  - enzymology
KW  - Myocardium
KW  - Myocytes, Cardiac
KW  - Proteolysis
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1126/science.aad0116
ER  -