TY  - GEN
AU  - Harraz,M M
AU  - Tyagi,R
AU  - Cortés,P
AU  - Snyder,S H
TI  - Antidepressant action of ketamine via mTOR is mediated by inhibition of nitrergic Rheb degradation
SN  - 1476-5578
PY  - 2016///1114
KW  - Animals
KW  - Antidepressive Agents
KW  - pharmacology
KW  - Cells, Cultured
KW  - Cerebral Cortex
KW  - cytology
KW  - Cysteine
KW  - analogs & derivatives
KW  - Depression
KW  - drug therapy
KW  - Disease Models, Animal
KW  - Embryo, Mammalian
KW  - Exploratory Behavior
KW  - drug effects
KW  - Female
KW  - Gene Expression Regulation
KW  - HEK293 Cells
KW  - Humans
KW  - Ketamine
KW  - Male
KW  - Mice, Inbred C57BL
KW  - Mice, Knockout
KW  - Monomeric GTP-Binding Proteins
KW  - genetics
KW  - N-Methylaspartate
KW  - Neurons
KW  - Neuropeptides
KW  - Nitric Oxide
KW  - Nitric Oxide Synthase Type I
KW  - deficiency
KW  - Nitric Oxide Synthase Type II
KW  - Pregnancy
KW  - Proteolysis
KW  - Ras Homolog Enriched in Brain Protein
KW  - S-Nitrosothiols
KW  - Signal Transduction
KW  - Swimming
KW  - psychology
KW  - TOR Serine-Threonine Kinases
KW  - Time Factors
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1038/mp.2015.211
ER  -