TY  - GEN
AU  - Lood,Christian
AU  - Blanco,Luz P
AU  - Purmalek,Monica M
AU  - Carmona-Rivera,Carmelo
AU  - De Ravin,Suk S
AU  - Smith,Carolyne K
AU  - Malech,Harry L
AU  - Ledbetter,Jeffrey A
AU  - Elkon,Keith B
AU  - Kaplan,Mariana J
TI  - Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease
SN  - 1546-170X
PY  - 2016///0627
KW  - Adult
KW  - Animals
KW  - Antigen-Antibody Complex
KW  - DNA, Mitochondrial
KW  - metabolism
KW  - Extracellular Traps
KW  - immunology
KW  - Female
KW  - Granulomatous Disease, Chronic
KW  - genetics
KW  - Humans
KW  - Immunoprecipitation
KW  - In Vitro Techniques
KW  - Interferon Type I
KW  - Jurkat Cells
KW  - Kidney
KW  - Lupus Erythematosus, Systemic
KW  - Male
KW  - Mice
KW  - Microscopy, Fluorescence
KW  - Mitochondria
KW  - NADPH Oxidases
KW  - Neutrophils
KW  - Oxidation-Reduction
KW  - Peroxidase
KW  - Reactive Oxygen Species
KW  - Real-Time Polymerase Chain Reaction
KW  - Ribonucleoproteins
N1  - Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/nm.4027
ER  -