TY - GEN AU - Grohar,Patrick J AU - Kim,Suntae AU - Rangel Rivera,Guillermo O AU - Sen,Nirmalya AU - Haddock,Sara AU - Harlow,Matt L AU - Maloney,Nichole K AU - Zhu,Jack AU - O'Neill,Maura AU - Jones,Tamara L AU - Huppi,Konrad AU - Grandin,Magdalena AU - Gehlhaus,Kristen AU - Klumpp-Thomas,Carleen A AU - Buehler,Eugen AU - Helman,Lee J AU - Martin,Scott E AU - Caplen,Natasha J TI - Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma SN - 2211-1247 PY - 2016///1020 KW - Base Sequence KW - Binding Sites KW - Calmodulin-Binding Proteins KW - antagonists & inhibitors KW - Cell Line, Tumor KW - Cell Survival KW - Exons KW - Gene Expression Regulation, Neoplastic KW - Heterogeneous-Nuclear Ribonucleoprotein Group F-H KW - Humans KW - Microfilament Proteins KW - Oncogene Proteins, Fusion KW - Phosphoproteins KW - Proto-Oncogene Protein c-fli-1 KW - RNA Interference KW - RNA Precursors KW - metabolism KW - RNA Splicing KW - RNA Splicing Factors KW - RNA, Small Interfering KW - RNA-Binding Protein EWS KW - RNA-Binding Proteins KW - Receptors, Cytoplasmic and Nuclear KW - Ribonucleoprotein, U2 Small Nuclear KW - Sarcoma, Ewing KW - pathology KW - Trans-Activators KW - Transcription Factors N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.celrep.2015.12.063 ER -