Rodgers, David T <br/><br/>
Switch-mediated activation and retargeting of CAR-T cells for B-cell malignancies.  [electronic resource] 

 -  Proceedings of the National Academy of Sciences of the United States of America  Jan 2016 
 - E459-68 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural 
<br/><br/><label>ISSN: </label>1091-6490 
<br/><br/><label>Standard No.: </label>10.1073/pnas.1524155113  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antigens, CD19--immunology<br/>Antigens, Neoplasm--immunology<br/>Azides<br/>B-Lymphocytes--immunology<br/>Basic-Leucine Zipper Transcription Factors--immunology<br/>Cell Line, Tumor<br/>Cytokines--metabolism<br/>Cytotoxicity, Immunologic<br/>Dose-Response Relationship, Immunologic<br/>Female<br/>Genes, Reporter<br/>Genetic Vectors<br/>Humans<br/>Immunotherapy, Adoptive--adverse effects<br/>Leukemia, B-Cell--therapy<br/>Lymphocyte Activation<br/>Lymphopenia--etiology<br/>Mice<br/>Mice, Inbred C57BL<br/>Mice, Inbred NOD<br/>Mice, SCID<br/>Phenylalanine--analogs & derivatives<br/>Protein Engineering--methods<br/>Receptors, Antigen, T-Cell--genetics<br/>Recombinant Fusion Proteins--immunology<br/>Saccharomyces cerevisiae Proteins--immunology<br/>Sialic Acid Binding Ig-like Lectin 2--immunology<br/>Single-Chain Antibodies--genetics<br/>Structure-Activity Relationship<br/>T-Cell Antigen Receptor Specificity<br/>T-Lymphocyte Subsets--immunology<br/>Xenograft Model Antitumor Assays