Ma, Jennifer S Y
Versatile strategy for controlling the specificity and activity of engineered T cells. [electronic resource]
- Proceedings of the National Academy of Sciences of the United States of America Jan 2016
- E450-8 p. digital
Publication Type: Journal Article
ISSN: 1091-6490
Standard No.: 10.1073/pnas.1524193113 doi
Subjects--Topical Terms: Animals Antigens, CD19--immunology Antigens, Neoplasm--immunology Azides B-Lymphocytes--immunology Cell Line, Tumor Cytotoxicity, Immunologic Female Fluorescein-5-isothiocyanate Genetic Vectors Humans Immunotherapy, Adoptive--adverse effects Lentivirus--genetics Leukemia, B-Cell--therapy Lymphocyte Activation Lymphopenia--etiology Mice Mice, Inbred C57BL Mice, Inbred NOD Mice, SCID Models, Molecular Phenylalanine--analogs & derivatives Protein Conformation Protein Engineering--methods Receptors, Antigen, T-Cell--genetics Recombinant Fusion Proteins--immunology Sialic Acid Binding Ig-like Lectin 2--immunology Single-Chain Antibodies--genetics T-Cell Antigen Receptor Specificity T-Lymphocytes--immunology Transduction, Genetic Xenograft Model Antitumor Assays