TY  - GEN
AU  - Conceição,Mariana
AU  - Mendonça,Liliana
AU  - Nóbrega,Clévio
AU  - Gomes,Célia
AU  - Costa,Pedro
AU  - Hirai,Hirokazu
AU  - Moreira,João Nuno
AU  - Lima,Maria C
AU  - Manjunath,N
AU  - Pereira de Almeida,Luís
TI  - Intravenous administration of brain-targeted stable nucleic acid lipid particles alleviates Machado-Joseph disease neurological phenotype
SN  - 1878-5905
PY  - 2016///1020
KW  - Animals
KW  - Brain
KW  - drug effects
KW  - Drug Stability
KW  - Gene Silencing
KW  - Injections, Intravenous
KW  - Lipids
KW  - chemistry
KW  - Liposomes
KW  - Machado-Joseph Disease
KW  - genetics
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Nucleic Acids
KW  - administration & dosage
KW  - Particle Size
KW  - Phenotype
KW  - RNA, Small Interfering
KW  - Treatment Outcome
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.biomaterials.2015.12.021
ER  -