Mugnaini, Claudia <br/><br/>
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 7. Synthesis and Pharmacological Evaluation of 4-Quinolone-3-carboxamides and 4-Hydroxy-2-quinolone-3-carboxamides as High Affinity Cannabinoid Receptor 2 (CB2R) Ligands with Improved Aqueous Solubility.  [electronic resource] 

 -  Journal of medicinal chemistry  Feb 2016 
 - 1052-67 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/acs.jmedchem.5b01559  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Cell Survival--drug effects<br/>Cells, Cultured<br/>Dose-Response Relationship, Drug<br/>Humans<br/>Ligands<br/>Mice<br/>Molecular Structure<br/>NIH 3T3 Cells<br/>Quinolones--chemical synthesis<br/>Receptor, Cannabinoid, CB2--antagonists & inhibitors<br/>Solubility<br/>Structure-Activity Relationship<br/>Water--chemistry