TY - GEN AU - Brock,Joseph S AU - Hamberg,Mats AU - Balagunaseelan,Navisraj AU - Goodman,Michael AU - Morgenstern,Ralf AU - Strandback,Emilia AU - Samuelsson,Bengt AU - Rinaldo-Matthis,Agnes AU - Haeggström,Jesper Z TI - A dynamic Asp-Arg interaction is essential for catalysis in microsomal prostaglandin E2 synthase SN - 1091-6490 PY - 2016///0617 KW - Catalysis KW - Catalytic Domain KW - Crystallography, X-Ray KW - Dipeptides KW - chemistry KW - Glutathione KW - metabolism KW - Intramolecular Oxidoreductases KW - Ligands KW - Microsomes KW - enzymology KW - Mutagenesis, Site-Directed KW - Prostaglandin-E Synthases KW - Protein Conformation N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1073/pnas.1522891113 ER -