Goniothalamin induces cell cycle arrest and apoptosis in H400 human oral squamous cell carcinoma: A caspase-dependent mitochondrial-mediated pathway with downregulation of NF-κβ. [electronic resource]
- Archives of oral biology Apr 2016
- 28-38 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1879-1506
10.1016/j.archoralbio.2015.12.002 doi
Antineoplastic Agents--pharmacology Apoptosis--drug effects Carcinoma, Squamous Cell--drug therapy Caspases--biosynthesis Cell Cycle Checkpoints--drug effects Cell Line, Tumor Cell Proliferation--drug effects Cytochromes c--metabolism Cytosol--metabolism Down-Regulation--drug effects Enzyme Induction Head and Neck Neoplasms--drug therapy Humans Membrane Potential, Mitochondrial--drug effects Metabolic Networks and Pathways--drug effects Mitochondria--drug effects Mouth Neoplasms--drug therapy NF-kappa B--metabolism Proto-Oncogene Proteins c-bcl-2--metabolism Pyrones--pharmacology S Phase--drug effects Squamous Cell Carcinoma of Head and Neck