Li, Lim K

Goniothalamin induces cell cycle arrest and apoptosis in H400 human oral squamous cell carcinoma: A caspase-dependent mitochondrial-mediated pathway with downregulation of NF-κβ. [electronic resource] - Archives of oral biology Apr 2016 - 28-38 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1879-1506

10.1016/j.archoralbio.2015.12.002 doi


Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Carcinoma, Squamous Cell--drug therapy
Caspases--biosynthesis
Cell Cycle Checkpoints--drug effects
Cell Line, Tumor
Cell Proliferation--drug effects
Cytochromes c--metabolism
Cytosol--metabolism
Down-Regulation--drug effects
Enzyme Induction
Head and Neck Neoplasms--drug therapy
Humans
Membrane Potential, Mitochondrial--drug effects
Metabolic Networks and Pathways--drug effects
Mitochondria--drug effects
Mouth Neoplasms--drug therapy
NF-kappa B--metabolism
Proto-Oncogene Proteins c-bcl-2--metabolism
Pyrones--pharmacology
S Phase--drug effects
Squamous Cell Carcinoma of Head and Neck