TY - GEN AU - Wouters,Mira M AU - Balemans,Dafne AU - Van Wanrooy,Sander AU - Dooley,James AU - Cibert-Goton,Vincent AU - Alpizar,Yeranddy A AU - Valdez-Morales,Eduardo E AU - Nasser,Yasmin AU - Van Veldhoven,Paul P AU - Vanbrabant,Winde AU - Van der Merwe,Schalk AU - Mols,Raf AU - Ghesquière,Bart AU - Cirillo,Carla AU - Kortekaas,Inge AU - Carmeliet,Peter AU - Peetermans,Willy E AU - Vermeire,Séverine AU - Rutgeerts,Paul AU - Augustijns,Patrick AU - Hellings,Peter W AU - Belmans,Ann AU - Vanner,Stephen AU - Bulmer,David C AU - Talavera,Karel AU - Vanden Berghe,Pieter AU - Liston,Adrian AU - Boeckxstaens,Guy E TI - Histamine Receptor H1-Mediated Sensitization of TRPV1 Mediates Visceral Hypersensitivity and Symptoms in Patients With Irritable Bowel Syndrome SN - 1528-0012 PY - 2016///0808 KW - Abdominal Pain KW - metabolism KW - Adolescent KW - Adult KW - Aged KW - Analgesics KW - adverse effects KW - Belgium KW - Biopsy KW - Butyrophenones KW - Calcium Signaling KW - drug effects KW - Double-Blind Method KW - Female KW - Gastrointestinal Agents KW - Histamine H1 Antagonists KW - Humans KW - Irritable Bowel Syndrome KW - diagnosis KW - Male KW - Middle Aged KW - Neurons KW - Pain Measurement KW - Pain Threshold KW - Piperidines KW - Quality of Life KW - Receptor Cross-Talk KW - Receptors, Histamine H1 KW - Rectum KW - innervation KW - Remission Induction KW - Surveys and Questionnaires KW - TRPV Cation Channels KW - Time Factors KW - Treatment Outcome KW - Young Adult N1 - Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1053/j.gastro.2015.12.034 ER -