Zimmer, Jutta <br/><br/>
Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds.  [electronic resource] 

 -  Molecular cell  Feb 2016 
 - 449-460 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1097-4164 
<br/><br/><label>Standard No.: </label>10.1016/j.molcel.2015.12.004  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Aminoquinolines--pharmacology<br/>Animals<br/>Antineoplastic Agents--pharmacology<br/>BRCA1 Protein--deficiency<br/>BRCA2 Protein--deficiency<br/>Biomarkers, Tumor--deficiency<br/>Cell Proliferation--drug effects<br/>DNA Breaks, Double-Stranded<br/>Dose-Response Relationship, Drug<br/>Drug Resistance, Neoplasm<br/>G-Quadruplexes--drug effects<br/>G2 Phase Cell Cycle Checkpoints--drug effects<br/>HEK293 Cells<br/>Humans<br/>Intracellular Signaling Peptides and Proteins--genetics<br/>Mad2 Proteins--genetics<br/>Male<br/>Mice, Nude<br/>Molecular Targeted Therapy<br/>Neoplasms--drug therapy<br/>Picolinic Acids--pharmacology<br/>Poly(ADP-ribose) Polymerase Inhibitors--pharmacology<br/>RNA Interference<br/>Telomere--drug effects<br/>Time Factors<br/>Transfection<br/>Tumor Burden--drug effects<br/>Tumor Suppressor p53-Binding Protein 1<br/>Xenograft Model Antitumor Assays