TY - GEN AU - Evans,Iona C AU - Barnes,Josephine L AU - Garner,Ian M AU - Pearce,David R AU - Maher,Toby M AU - Shiwen,Xu AU - Renzoni,Elisabetta A AU - Wells,Athol U AU - Denton,Christopher P AU - Laurent,Geoffrey J AU - Abraham,David J AU - McAnulty,Robin J TI - Epigenetic regulation of cyclooxygenase-2 by methylation of c8orf4 in pulmonary fibrosis SN - 1470-8736 PY - 2016///0718 KW - Aged KW - Binding Sites KW - Case-Control Studies KW - Cell Proliferation KW - Cells, Cultured KW - Cyclooxygenase 2 KW - genetics KW - DNA Methylation KW - drug effects KW - DNA Modification Methylases KW - antagonists & inhibitors KW - Dinoprostone KW - metabolism KW - Dose-Response Relationship, Drug KW - Down-Regulation KW - Enzyme Inhibitors KW - pharmacology KW - Epigenesis, Genetic KW - Female KW - Fibroblasts KW - Gene Expression Regulation, Neoplastic KW - Genotype KW - Humans KW - Lung KW - Male KW - Middle Aged KW - Neoplasm Proteins KW - Phenotype KW - Promoter Regions, Genetic KW - Pulmonary Fibrosis KW - enzymology KW - RNA Interference KW - RNA, Messenger KW - Scleroderma, Systemic KW - Transcription, Genetic KW - Transfection N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1042/CS20150697 ER -