TY - GEN AU - Shu,Shaokun AU - Lin,Charles Y AU - He,Housheng Hansen AU - Witwicki,Robert M AU - Tabassum,Doris P AU - Roberts,Justin M AU - Janiszewska,Michalina AU - Huh,Sung Jin AU - Liang,Yi AU - Ryan,Jeremy AU - Doherty,Ernest AU - Mohammed,Hisham AU - Guo,Hao AU - Stover,Daniel G AU - Ekram,Muhammad B AU - Brown,Jonathan AU - D'Santos,Clive AU - Krop,Ian E AU - Dillon,Deborah AU - McKeown,Michael AU - Ott,Christopher AU - Qi,Jun AU - Ni,Min AU - Rao,Prakash K AU - Duarte,Melissa AU - Wu,Shwu-Yuan AU - Chiang,Cheng-Ming AU - Anders,Lars AU - Young,Richard A AU - Winer,Eric AU - Letai,Antony AU - Barry,William T AU - Carroll,Jason S AU - Long,Henry AU - Brown,Myles AU - Liu,X Shirley AU - Meyer,Clifford A AU - Bradner,James E AU - Polyak,Kornelia TI - Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer SN - 1476-4687 PY - 2016///0428 KW - Animals KW - Azepines KW - pharmacology KW - Binding, Competitive KW - drug effects KW - Casein Kinase II KW - metabolism KW - Cell Cycle Proteins KW - Cell Line, Tumor KW - Cell Proliferation KW - Chromatin KW - genetics KW - Drug Resistance, Neoplasm KW - Epigenesis, Genetic KW - Female KW - Gene Expression Regulation, Neoplastic KW - Genome, Human KW - Humans KW - Mediator Complex Subunit 1 KW - Mice KW - Nuclear Proteins KW - antagonists & inhibitors KW - Phosphorylation KW - Phosphoserine KW - Protein Binding KW - Protein Phosphatase 2 KW - Protein Structure, Tertiary KW - Proteomics KW - Transcription Factors KW - Transcription, Genetic KW - Triazoles KW - Triple Negative Breast Neoplasms KW - drug therapy KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1038/nature16508 ER -