TY - GEN AU - Chen,Shih-Hsun AU - Zhang,Youyan AU - Van Horn,Robert D AU - Yin,Tinggui AU - Buchanan,Sean AU - Yadav,Vipin AU - Mochalkin,Igor AU - Wong,Swee Seong AU - Yue,Yong Gang AU - Huber,Lysiane AU - Conti,Ilaria AU - Henry,James R AU - Starling,James J AU - Plowman,Gregory D AU - Peng,Sheng-Bin TI - Oncogenic BRAF Deletions That Function as Homodimers and Are Sensitive to Inhibition by RAF Dimer Inhibitor LY3009120 SN - 2159-8290 PY - 2016///1213 KW - Animals KW - Antineoplastic Agents KW - chemistry KW - Cell Line, Tumor KW - Cell Transformation, Neoplastic KW - genetics KW - Disease Models, Animal KW - Drug Resistance, Neoplasm KW - Ectopic Gene Expression KW - Gene Deletion KW - Gene Expression KW - Humans KW - MAP Kinase Signaling System KW - Mice KW - Models, Molecular KW - Phenylurea Compounds KW - pharmacology KW - Protein Conformation KW - Protein Interaction Domains and Motifs KW - Protein Kinase Inhibitors KW - Protein Multimerization KW - Proto-Oncogene Proteins B-raf KW - antagonists & inhibitors KW - Pyrimidines KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article UR - https://doi.org/10.1158/2159-8290.CD-15-0896 ER -