TY  - GEN
AU  - Neil,Jayson
AU  - Shannon,Craig
AU  - Mohan,Avinash
AU  - Laurent,Dimitri
AU  - Murali,Raj
AU  - Jhanwar-Uniyal,Meena
TI  - ATP-site binding inhibitor effectively targets mTORC1 and mTORC2 complexes in glioblastoma
SN  - 1791-2423
PY  - 2016///1213
KW  - Adenosine Triphosphate
KW  - chemistry
KW  - Binding, Competitive
KW  - Brain Neoplasms
KW  - metabolism
KW  - Cell Line, Tumor
KW  - Cell Movement
KW  - Cell Proliferation
KW  - Cell Survival
KW  - Chemotaxis
KW  - Extracellular Signal-Regulated MAP Kinases
KW  - Glioblastoma
KW  - Humans
KW  - Indoles
KW  - Insulin
KW  - Mechanistic Target of Rapamycin Complex 1
KW  - Mechanistic Target of Rapamycin Complex 2
KW  - Multiprotein Complexes
KW  - Phenotype
KW  - Phosphorylation
KW  - drug effects
KW  - Protein Binding
KW  - Purines
KW  - S Phase
KW  - Signal Transduction
KW  - Sirolimus
KW  - TOR Serine-Threonine Kinases
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.3892/ijo.2015.3311
ER  -