Yousef, Bashir A

Pristimerin demonstrates anticancer potential in colorectal cancer cells by inducing G1 phase arrest and apoptosis and suppressing various pro-survival signaling proteins. [electronic resource] - Oncology reports Feb 2016 - 1091-100 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1791-2431

10.3892/or.2015.4457 doi


Adenocarcinoma--pathology
Antineoplastic Agents, Phytogenic--pharmacology
Apoptosis--drug effects
Apoptosis Regulatory Proteins--biosynthesis
Cell Cycle Proteins--biosynthesis
Cell Line, Tumor
Colorectal Neoplasms--pathology
Drug Screening Assays, Antitumor
G1 Phase--drug effects
Gene Expression Regulation, Neoplastic--drug effects
Humans
Intracellular Signaling Peptides and Proteins--biosynthesis
Membrane Potential, Mitochondrial--drug effects
Neoplasm Proteins--biosynthesis
Pentacyclic Triterpenes
Signal Transduction--drug effects
Triterpenes--pharmacology