Goyard, David <br/><br/>
Glucose-derived spiro-isoxazolines are anti-hyperglycemic agents against type 2 diabetes through glycogen phosphorylase inhibition.  [electronic resource] 

 -  European journal of medicinal chemistry  Jan 2016 
 - 444-454 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1768-3254 
<br/><br/><label>Standard No.: </label>10.1016/j.ejmech.2015.12.004  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Diabetes Mellitus, Experimental--drug therapy<br/>Diabetes Mellitus, Type 2--drug therapy<br/>Disease Models, Animal<br/>Dose-Response Relationship, Drug<br/>Enzyme Inhibitors--chemical synthesis<br/>Glucose--analogs & derivatives<br/>Glycogen Phosphorylase--antagonists & inhibitors<br/>Hypoglycemic Agents--chemical synthesis<br/>Isoxazoles--chemical synthesis<br/>Molecular Structure<br/>Rats<br/>Rats, Zucker<br/>Spiro Compounds--chemical synthesis<br/>Structure-Activity Relationship