TY - GEN AU - Cheng,Jianjun AU - Giguere,Patrick M AU - Schmerberg,Claire M AU - Pogorelov,Vladimir M AU - Rodriguiz,Ramona M AU - Huang,Xi-Ping AU - Zhu,Hu AU - McCorvy,John D AU - Wetsel,William C AU - Roth,Bryan L AU - Kozikowski,Alan P TI - Further Advances in Optimizing (2-Phenylcyclopropyl)methylamines as Novel Serotonin 2C Agonists: Effects on Hyperlocomotion, Prepulse Inhibition, and Cognition Models SN - 1520-4804 PY - 2016///0614 KW - Animals KW - Brain KW - metabolism KW - Catalepsy KW - chemically induced KW - Central Nervous System Stimulants KW - Cognition KW - drug effects KW - Dextroamphetamine KW - Drug Design KW - Drug Evaluation, Preclinical KW - Ether-A-Go-Go Potassium Channels KW - antagonists & inhibitors KW - Female KW - Humans KW - Hyperkinesis KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Microsomes, Liver KW - Prepulse Inhibition KW - Receptor, Serotonin, 5-HT2C KW - Recognition, Psychology KW - Schizophrenia KW - drug therapy KW - Schizophrenic Psychology KW - Serotonin 5-HT2 Receptor Agonists KW - chemical synthesis KW - Structure-Activity Relationship KW - Substrate Specificity N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1021/acs.jmedchem.5b01153 ER -