TY - GEN AU - Bolduc,David M AU - Montagna,Daniel R AU - Gu,Yongli AU - Selkoe,Dennis J AU - Wolfe,Michael S TI - Nicastrin functions to sterically hinder γ-secretase-substrate interactions driven by substrate transmembrane domain SN - 1091-6490 PY - 2016///0815 KW - Amyloid Precursor Protein Secretases KW - metabolism KW - Lipid Bilayers KW - Membrane Glycoproteins KW - physiology KW - Substrate Specificity N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1073/pnas.1512952113 ER -