Osorio, Fernando G <br/><br/>
Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling.  [electronic resource] 

 -  Nature medicine  Jan 2016 
 - 91-6 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1546-170X 
<br/><br/><label>Standard No.: </label>10.1038/nm.4013  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adaptor Proteins, Signal Transducing<br/>Animals<br/>Blotting, Western<br/>CRISPR-Cas Systems<br/>Caenorhabditis elegans<br/>Caenorhabditis elegans Proteins--genetics<br/>Carrier Proteins--genetics<br/>Flow Cytometry<br/>Fluorescent Antibody Technique<br/>Humans<br/>Immunoprecipitation<br/>Insulin-Like Growth Factor I--metabolism<br/>Mice<br/>Mice, Knockout<br/>Microfilament Proteins--genetics<br/>Myeloproliferative Disorders--genetics<br/>Proteasome Endopeptidase Complex--metabolism<br/>Proteomics<br/>Proteostasis Deficiencies<br/>RNA-Binding Proteins--genetics<br/>Real-Time Polymerase Chain Reaction<br/>Receptor, IGF Type 1--metabolism<br/>Receptor, Insulin--genetics<br/>Signal Transduction<br/>Ubiquitination<br/>Zinc Fingers--genetics