TY - GEN AU - Aylett,Christopher H S AU - Sauer,Evelyn AU - Imseng,Stefan AU - Boehringer,Daniel AU - Hall,Michael N AU - Ban,Nenad AU - Maier,Timm TI - Architecture of human mTOR complex 1 SN - 1095-9203 PY - 2016///0119 KW - Adaptor Proteins, Signal Transducing KW - chemistry KW - Catalytic Domain KW - Cryoelectron Microscopy KW - Humans KW - Mechanistic Target of Rapamycin Complex 1 KW - Mechanistic Target of Rapamycin Complex 2 KW - Multiprotein Complexes KW - Protein Binding KW - Protein Multimerization KW - Protein Structure, Secondary KW - Protein Structure, Tertiary KW - Regulatory-Associated Protein of mTOR KW - Substrate Specificity KW - TOR Serine-Threonine Kinases KW - Tacrolimus Binding Proteins KW - mTOR Associated Protein, LST8 Homolog N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1126/science.aaa3870 ER -