Ju, Ling-sha

Hypermethylation of Hippocampal Synaptic Plasticity-Related genes is Involved in Neonatal Sevoflurane Exposure-Induced Cognitive Impairments in Rats. [electronic resource] - Neurotoxicity research Feb 2016 - 243-55 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1476-3524

10.1007/s12640-015-9585-1 doi


Anesthetics, Inhalation--administration & dosage
Animals
Animals, Newborn
Azacitidine--administration & dosage
Brain-Derived Neurotrophic Factor--genetics
Cell Adhesion Molecules, Neuronal--genetics
Cognition Disorders--chemically induced
Conditioning, Psychological--drug effects
DNA Methylation
DNA Modification Methylases--antagonists & inhibitors
Decitabine
Dendritic Spines--drug effects
Extracellular Matrix Proteins--genetics
Fear--drug effects
Hippocampus--drug effects
Male
Maze Learning--drug effects
Methyl Ethers--administration & dosage
Methyl-CpG-Binding Protein 2--metabolism
Nerve Tissue Proteins--genetics
Neuronal Plasticity--drug effects
Pyramidal Cells--drug effects
RNA, Messenger--metabolism
Rats
Rats, Sprague-Dawley
Reelin Protein
Serine Endopeptidases--genetics
Sevoflurane