TY  - GEN
AU  - Zhao,Jinghui
AU  - Zhai,Bo
AU  - Gygi,Steven P
AU  - Goldberg,Alfred Lewis
TI  - mTOR inhibition activates overall protein degradation by the ubiquitin proteasome system as well as by autophagy
SN  - 1091-6490
PY  - 2016///0811
KW  - Animals
KW  - Autophagy
KW  - Blotting, Western
KW  - Cells, Cultured
KW  - HEK293 Cells
KW  - Humans
KW  - Hydroxymethylglutaryl-CoA Synthase
KW  - metabolism
KW  - Immunosuppressive Agents
KW  - pharmacology
KW  - Naphthyridines
KW  - Proteasome Endopeptidase Complex
KW  - Proteolysis
KW  - drug effects
KW  - Sirolimus
KW  - TOR Serine-Threonine Kinases
KW  - antagonists & inhibitors
KW  - Time Factors
KW  - Ubiquitin
KW  - Ubiquitination
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1073/pnas.1521919112
ER  -